Description

3-Bromo-Pyridine-4-Sulfonyl Chloride is a versatile and highly reactive heterocyclic building block essential for advanced organic synthesis. Its core value lies in the sulfonyl chloride functional group, which readily undergoes nucleophilic substitution, enabling the efficient construction of sulfonamides and sulfonate esters. This compound is critically needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides with sulfonyl-containing bioactive moieties.
• Material Science Research: Serves as a building block for creating functionalized polymers and advanced materials with specific surface properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of activity-based probes targeting specific enzymes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring the introduction of a bromo-pyridine-sulfonyl scaffold.
• Library Synthesis for Drug Discovery: Facilitates high-throughput parallel synthesis to create diverse compound libraries for screening against biological targets.

Basic Information

Product Name	3-Bromo-Pyridine-4-Sulfonyl Chloride
CAS No.	886371-33-1
Molecular Formula	C5H3BrClNO2S
Molecular Weight	256.50 g/mol
Synonyms	4-Pyridinesulfonyl chloride, 3-bromo-; 3-Bromo-4-pyridinesulfonyl chloride; 3-Bromopyridine-4-sulfonyl chloride; 886371-33-1; 3-Bromo-4-(chlorosulfonyl)pyridine; 4-Chlorosulfonyl-3-bromopyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-Pyridine-4-Sulfonyl Chloride is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.