Description

C-(3-Trifluoromethyl-Pyridin-2-Yl)-Methylamine is a high-value, fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs), particularly due to the unique properties imparted by the trifluoromethyl and amine functional groups. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small molecule drugs, especially kinase inhibitors, receptor antagonists, and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Ligand & Catalyst Preparation: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic or surface properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	C-(3-Trifluoromethyl-Pyridin-2-Yl)-Methylamine
CAS No.	886371-24-0
Molecular Formula	C7H7F3N2
Molecular Weight	176.14 g/mol
Synonyms	1-(3-(Trifluoromethyl)pyridin-2-yl)methanamine; (3-Trifluoromethyl-2-pyridinyl)methylamine; 2-(Aminomethyl)-3-(trifluoromethyl)pyridine; α-Amino-3-(trifluoromethyl)-2-picoline; 2-Pyridinemethanamine, 3-(trifluoromethyl)-; C-(3-Trifluoromethylpyridin-2-yl)methylamine
EINECS	Contact for details

Quality Control

Our C-(3-Trifluoromethyl-Pyridin-2-Yl)-Methylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.