Description

6-Bromo-Pyridine-3-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. Its value lies in enabling the efficient introduction of the sulfonamide functional group, a key motif in the development of active pharmaceutical ingredients and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel sulfonamide-based compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-containing drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with sulfonamide backbones.
• Material Science: Serves as a monomer or cross-linking agent in the creation of functional polymers and advanced materials.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes and molecular tools for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic & Industrial R&D: Fundamental research reagent for exploring new synthetic methodologies and reaction pathways involving heterocyclic sulfonyl chlorides.

Basic Information

Product Name	6-Bromo-Pyridine-3-Sulfonyl Chloride
CAS No.	886371-20-6
Molecular Formula	C5H3BrClNO2S
Molecular Weight	256.51 g/mol
Synonyms	3-Bromo-5-(chlorosulfonyl)pyridine; 5-Bromopyridine-3-sulfonyl chloride; 6-Bromo-3-pyridinesulfonyl chloride; 6-Bromopyridine-3-sulfonyl chloride; 886371-20-6; Pyridine, 6-bromo-3-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 6-Bromo-Pyridine-3-Sulfonyl Chloride is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.