Description

3,5-Dichloro-Pyridine-2-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, enabling the introduction of both a sulfonamide linkage and a halogenated pyridine scaffold into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used to construct active ingredients for herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine-sulfonamide core.
• Chemical Research & Development: A versatile reagent for constructing complex heterocyclic compounds and exploring new reaction pathways in medicinal chemistry.
• Material Science: Potential monomer or cross-linking agent for creating specialized polymers with unique thermal or chemical resistance properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke molecules and development compounds under cGMP guidelines where required.

Basic Information

Product Name	3,5-Dichloro-Pyridine-2-Sulfonyl Chloride
CAS No.	886371-16-0
Molecular Formula	C5H2Cl3NO2S
Molecular Weight	246.50 g/mol
Synonyms	2,5-Dichloropyridine-3-sulfonyl chloride; 3,5-Dichloropyridine-2-sulfonyl chloride; 2-Pyridinesulfonyl chloride, 3,5-dichloro-; 3,5-Dichloro-2-pyridinesulfonyl chloride; 886371-16-0; 3,5-Dichloro-2-pyridylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3,5-Dichloro-Pyridine-2-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing specific results for purity, identity, and related substances is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.