Description

1-(4-Fluoropyridin-3-Yl)Ethanone is a high-purity fluorinated pyridine derivative, a critical building block in modern organic synthesis. Its value lies in its unique structure, which serves as a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced materials, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials due to the electron-withdrawing nature of the fluoropyridine moiety.
• Chemical Biology & Proteomics: Employed as a building block for creating molecular probes and affinity tags to study biological systems.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring fluorinated heterocyclic scaffolds.

Basic Information

Product Name	1-(4-Fluoropyridin-3-Yl)Ethanone
CAS No.	886364-63-2
Molecular Formula	C7H6FNO
Molecular Weight	139.13 g/mol
Synonyms	3-Acetyl-4-fluoropyridine; 4-Fluoro-3-acetylpyridine; 1-(4-Fluoropyridin-3-yl)ethan-1-one; 1-(4-Fluoro-3-pyridinyl)ethanone; Ethanone, 1-(4-fluoro-3-pyridinyl)-; 886364-63-2; 4-Fluoropyridin-3-yl methyl ketone
EINECS	Contact for details

Quality Control

Our 1-(4-Fluoropyridin-3-Yl)Ethanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC, GC, NMR, and mass spectrometry, to verify identity and purity. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality protocols are designed to meet the stringent requirements of GMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.