Description

4-[3,5-Bis(Trifluoromethyl)Phenoxy]Benzenesulfonyl Chloride is a high-value, specialized organofluorine building block and sulfonylating agent. Its molecular structure, featuring a sulfonyl chloride group and electron-deficient trifluoromethyl-substituted aromatic rings, makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise functionalization to develop novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, particularly in areas like kinase inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in creating advanced herbicides and pesticides where the trifluoromethyl group imparts improved metabolic stability and lipophilicity.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and membranes with unique chemical resistance.
• Chemical Research: A versatile reagent in organic synthesis for introducing the sulfonyl chloride functional group into complex molecules for further derivatization.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis, leveraging the electron-withdrawing character of the trifluoromethyl groups.

Basic Information

Product Name	4-[3,5-Bis(Trifluoromethyl)Phenoxy]Benzenesulfonyl Chloride
CAS No.	885950-90-3
Molecular Formula	C15H7ClF6O3S
Molecular Weight	416.72 g/mol
Synonyms	4-[3,5-Bis(trifluoromethyl)phenoxy]benzenesulfonyl chloride; 1-[3,5-Bis(trifluoromethyl)phenoxy]-4-chlorosulfonylbenzene; p-[3,5-Bis(trifluoromethyl)phenoxy]benzenesulfonyl chloride; 4-(3,5-Bis(trifluoromethyl)phenoxy)benzene-1-sulfonyl chloride; Benzenesulfonyl chloride, 4-[3,5-bis(trifluoromethyl)phenoxy]-; 885950-90-3
EINECS	Contact for details

Quality Control

Our 4-[3,5-Bis(Trifluoromethyl)Phenoxy]Benzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for specific impurities. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.