Description

2-(5-Fluoro-Pyridin-2-Yl)-Phenylamine is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure makes it a valuable intermediate for the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific fluorinated motifs into complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the fluoropyridine moiety enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes, including cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or fluorinated polymers for specialized applications.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags or molecular probes for diagnostic and research purposes.

Basic Information

Product Name	2-(5-Fluoro-Pyridin-2-Yl)-Phenylamine
CAS No.	885277-17-8
Molecular Formula	C11H9FN2
Molecular Weight	188.20 g/mol
Synonyms	2-(5-Fluoropyridin-2-yl)aniline; 2-Amino-5'-fluorobiphenyl-2'-amine; 2-(5-Fluoro-2-pyridinyl)benzenamine; 2-(5-Fluoropyridin-2-yl)phenylamine; 5'-Fluoro-[1,1'-biphenyl]-2-amine; 2-(5-Fluoropyridin-2-yl)aniline; 2-Pyridinamine, 5-fluoro-N-phenyl-; [1,1'-Biphenyl]-2-amine, 5'-fluoro-
EINECS	Contact for details

Quality Control

Our 2-(5-Fluoro-Pyridin-2-Yl)-Phenylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical and agrochemical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.