Description

1-Chloro-2,4-Difluoro-5-Methyl-Benzene is a high-purity, multi-substituted aromatic building block of significant importance in advanced organic synthesis. Its unique halogenated structure makes it a critical intermediate for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers seeking to introduce specific fluorine and chlorine motifs into target structures, enabling the fine-tuning of biological activity and material properties.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs containing difluorobenzene and chlorobenzene motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where halogenated aromatic rings enhance efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Employed as a monomer or modifier in the synthesis of high-performance polymers and resins with specific thermal and chemical resistance.
• Chemical Research & Development: A versatile building block for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) in academic and industrial R&D laboratories.
• Dye & Pigment Industry: Acts as an intermediate in the synthesis of complex dyes and organic pigments.

Basic Information

Product Name	1-Chloro-2,4-Difluoro-5-Methyl-Benzene
CAS No.	885267-23-2
Molecular Formula	C7H5ClF2
Molecular Weight	162.56 g/mol
Synonyms	2,4-Difluoro-5-methylchlorobenzene; 5-Methyl-2,4-difluorochlorobenzene; 1-Chloro-2,4-difluoro-5-methylbenzene; 2-Chloro-1,3-difluoro-4-methylbenzene; Benzene, 1-chloro-2,4-difluoro-5-methyl-; 885267-23-2
EINECS	Contact for details

Quality Control

Our 1-Chloro-2,4-Difluoro-5-Methyl-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting compliance in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from strong bases and incompatible materials. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.30 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.