Description

Pgd2-Inhibitor CAS NO 885066-67-1 is a high-purity, small molecule compound designed to selectively target and inhibit Prostaglandin D2 (PGD2) signaling pathways. This targeted inhibition is crucial for research and development in inflammatory and allergic conditions, where PGD2 is a key mediator. It is an essential tool for pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on developing novel therapeutics for asthma, allergic rhinitis, and other mast cell-driven diseases.

Application

• Pharmaceutical Research & Development: A key reference standard and active ingredient in preclinical studies for novel anti-inflammatory and anti-allergy drug candidates.
• Biochemical Assay Development: Used as a selective inhibitor to validate assay systems and study PGD2 receptor (DP1/DP2) pharmacology and downstream signaling cascades.
• Academic & Institutional Research: Employed in mechanistic studies to elucidate the role of PGD2 in immune responses, mast cell activation, and chronic inflammatory disease models.
• Drug Discovery Screening: Serves as a positive control or tool compound in high-throughput screening (HTS) campaigns to identify new chemical entities targeting the PGD2 pathway.
• Inflammation & Immunology Studies: Critical for in vitro and in vivo research exploring therapeutic interventions for conditions like asthma, atopic dermatitis, and allergic conjunctivitis.

Basic Information

Product Name	Pgd2-Inhibitor CAS NO 885066-67-1
CAS No.	885066-67-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PGD2 Inhibitor; Prostaglandin D2 Inhibitor; DP receptor antagonist; CRTH2 antagonist; (3-((4-Fluorophenyl)sulfonyl)-2-methyl-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-4-yl)acetic acid (example IUPAC); 885066-67-1; PGD2 blocker; Anti-PGD2 compound
EINECS	Contact for details

Quality Control

Our Pgd2-Inhibitor is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity suitable for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.