Description

6-Phenyl-3-Pyridinesulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. This compound matters for its role as a key sulfonylation reagent, enabling the introduction of the sulfonyl functional group into complex molecular architectures. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides that utilize the sulfonyl moiety for enhanced biological activity.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialty polymers and functionalized surfaces.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling proteins or modifying biomolecules in research applications.
• Organic Synthesis Reagent: Facilitates sulfonylation reactions to construct carbon-sulfur bonds in complex molecule assembly.
• Ligand & Catalyst Development: Used to synthesize novel sulfonated ligands for metal complexes and catalytic systems.

Basic Information

Product Name	6-Phenyl-3-Pyridinesulfonyl Chloride
CAS No.	884507-12-4
Molecular Formula	C11H8ClNO2S
Molecular Weight	253.70 g/mol
Synonyms	3-Pyridinesulfonyl chloride, 6-phenyl-; 6-Phenylpyridine-3-sulfonyl chloride; 6-Phenyl-3-pyridylsulfonyl chloride; 884507-12-4; 3-(Chlorosulfonyl)-6-phenylpyridine; 6-Phenylnicotinic acid sulfonyl chloride (related); Phenylpyridinesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 6-Phenyl-3-Pyridinesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical data are provided with every shipment to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.