Description

3-Fluoro-2-Formyl-6-Methylpyridine is a high-purity, multi-functional pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both formyl and fluoro substituents, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce key functional groups into target molecules, enabling the discovery of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom enhances biological activity, metabolic stability, and lipophilicity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized nitrogen-containing ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the creation of functionalized polymers and organic electronic materials due to its reactive aldehyde group.
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for studying biological processes and enzyme mechanisms.
• Custom Synthesis and Contract Manufacturing: A valuable scaffold for custom chemical synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	3-Fluoro-2-Formyl-6-Methylpyridine
CAS No.	884495-48-1
Molecular Formula	C7H6FNO
Molecular Weight	139.13 g/mol
Synonyms	6-Methyl-3-fluoropyridine-2-carboxaldehyde; 2-Formyl-3-fluoro-6-methylpyridine; 3-Fluoro-6-methyl-2-pyridinecarboxaldehyde; 3-Fluoro-2-pyridinecarboxaldehyde, 6-methyl-; 3-Fluoro-6-methylpicolinaldehyde; 3-Fluoro-6-methyl-2-formylpyridine; 2-Aldehyde-3-fluoro-6-methylpyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-2-Formyl-6-Methylpyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Specifications can be tailored to meet specific research or cGMP starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.