Description

3-Fluoro-6-Formyl-2-Picoline is a high-value, multi-functional heterocyclic building block characterized by its reactive aldehyde and fluorine substituents on the pyridine ring. This compound matters for its critical role in facilitating the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile starting material for creating complex chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of functional organic materials, such as organic semiconductors and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or affinity probes to study biological systems and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring advanced fluorinated pyridine chemistry.

Basic Information

Product Name	3-Fluoro-6-Formyl-2-Picoline
CAS No.	884495-34-5
Molecular Formula	C7H6FNO
Molecular Weight	139.13 g/mol
Synonyms	2-Methyl-3-fluoro-6-pyridinecarboxaldehyde; 3-Fluoro-2-methyl-6-pyridinecarboxaldehyde; 3-Fluoro-2-picoline-6-carboxaldehyde; 6-Formyl-3-fluoro-2-picoline; 3-Fluoro-6-formyl-2-methylpyridine; 2-Methyl-3-fluoropyridine-6-carbaldehyde; 3-Fluoro-2-methylpyridine-6-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 3-Fluoro-6-Formyl-2-Picoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.