Description

6-Fluoro-3-Iodo-2-Methylpyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a versatile intermediate for introducing functional complexity into target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated heterocycles.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) to form complex biaryl systems.
• Fluorine Chemistry Building Block: The fluorine atom provides metabolic stability and influences lipophilicity, making it valuable for structure-activity relationship (SAR) studies in drug discovery.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	6-Fluoro-3-Iodo-2-Methylpyridine
CAS No.	884495-23-2
Molecular Formula	C6H5F I N
Molecular Weight	237.01 g/mol
Synonyms	2-Methyl-6-fluoro-3-iodopyridine; 3-Iodo-6-fluoro-2-methylpyridine; 6-Fluoro-2-methyl-3-iodopyridine; 2-Methyl-3-iodo-6-fluoropyridine; 884495-23-2; Pyridine, 6-fluoro-3-iodo-2-methyl-; Fluoromethyl iodopyridine intermediate
EINECS	Contact for details

Quality Control

Our 6-Fluoro-3-Iodo-2-Methylpyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality supports your R&D and scale-up processes with reliable, high-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.