Description

6-Fluoro-2-Methylnicotinic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a carboxylic acid group on the pyridine ring, makes it an essential intermediate for creating novel compounds with targeted biological activity. This product is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced metabolic stability and bioavailability.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: A versatile scaffold for contract research organizations (CROs) and custom synthesis houses to build specialized compound libraries.

Basic Information

Product Name	6-Fluoro-2-Methylnicotinic Acid
CAS No.	884494-97-7
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	2-Methyl-6-fluoronicotinic acid; 6-Fluoro-2-picolinic acid; 6-Fluoro-2-methylpyridine-3-carboxylic acid; 3-Carboxy-6-fluoro-2-methylpyridine; 884494-97-7; 6-Fluoro-2-methyl-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2-Methylnicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide full traceability and detailed Certificates of Analysis (COA) with every shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The container must be kept tightly closed in a dry and well-ventilated place due to its sensitivity to light and organic solvent/strong acid nature.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.