Description

5-Fluoro-2-Hydroxynicotinic Acid is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its unique molecular structure, which combines a fluorinated pyridine ring with both hydroxyl and carboxylic acid functional groups, enabling precise chemical modifications. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Ligand and Chelating Agent: Serves as a versatile building block for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes to study enzyme function and biological pathways.
• Fine Chemical Production: Acts as a critical intermediate for the custom synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	5-Fluoro-2-Hydroxynicotinic Acid
CAS No.	884494-83-1
Molecular Formula	C6H4FNO3
Molecular Weight	157.10 g/mol
Synonyms	2-Hydroxy-5-fluoronicotinic acid; 5-Fluoro-2-hydroxypyridine-3-carboxylic acid; 3-Carboxy-5-fluoro-2-hydroxypyridine; 5-Fluoro-2-pyridinol-3-carboxylic acid; 5-Fluoro-2-oxo-1,2-dihydropyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Hydroxynicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.