Description

3-Fluoro-2-Methoxypyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and methoxy substituents, enables precise modulation of electronic and steric properties in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for improved biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for constructing sophisticated ligands in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create fluorinated analogs of bioactive molecules for metabolic pathway studies and imaging.

Basic Information

Item	Details
Product Name	3-Fluoro-2-Methoxypyridine
CAS No.	884494-69-3
Molecular Formula	C6H6FNO
Molecular Weight	127.11 g/mol
Synonyms	2-Methoxy-3-fluoropyridine; 3-Fluoro-2-pyridinol methyl ether; 3-Fluoro-2-methoxypyridine; 3-Fluoro-2(1H)-pyridinone, methyl ether; 3-Fluoropyridin-2-ol methyl ether
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Methoxypyridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its fluoride/strong alkali chemical property, ensure proper segregation in storage areas.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.