Description

Fbpase-1 Inhibitor CAS NO 883973-99-7 is a potent and selective small molecule inhibitor of fructose-1,6-bisphosphatase-1 (FBPase-1), a key enzyme in the gluconeogenesis pathway. This compound is a critical research tool for investigating metabolic disorders, particularly type 2 diabetes, by targeting hepatic glucose production. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in metabolic disease research and novel therapeutic development.

Application

• Pharmaceutical Research & Development: A key reference standard and active compound for developing novel anti-diabetic therapeutics targeting gluconeogenesis.
• Metabolic Disease Studies: Used in in vitro and in vivo models to study the role of FBPase-1 in glucose homeostasis and insulin resistance.
• Biochemical Assay Development: Serves as a positive control and validation tool in high-throughput screening (HTS) campaigns for FBPase-1 activity.
• Mechanism of Action (MoA) Investigations: Employed to elucidate downstream signaling pathways and metabolic effects following FBPase-1 inhibition.
• Academic Research: Fundamental research into liver metabolism, enzyme kinetics, and the biochemical basis of diabetes.

Basic Information

Product Name	Fbpase-1 Inhibitor
CAS No.	883973-99-7
Molecular Formula	C₂₀H₂₀N₄O₃S
Molecular Weight	396.46 g/mol
Synonyms	MB06322; CS-917; Fructose-1,6-bisphosphatase inhibitor; FBPase inhibitor; (2R)-2-[(4aR,6R,7aS)-6-Hydroxy-2-(phenylsulfonyl)octahydrocyclopenta[d][1,3]oxazin-7a-yl]-N-(1H-imidazol-2-ylmethyl)acetamide; FBP1 Inhibitor
EINECS	Contact for details

Quality Control

Our Fbpase-1 Inhibitor is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and safety parameters is provided with every shipment to ensure reproducibility and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.