Description

3-Fluoro-2-Iodotoluene is a versatile halogenated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic positioning of fluorine and iodine atoms on the toluene scaffold, enabling selective functionalization for complex molecule construction. This compound is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and drug candidates, leveraging the fluorine atom for metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the fluorine substituent can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic electronic materials, where halogen atoms influence molecular polarity and packing.
• Cross-Coupling Reactions: The iodine atom acts as an excellent handle for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings to form biaryl and other complex structures.
• Fluorination Chemistry Studies: Utilized as a model substrate in methodological development for further functionalization or fluorination transfer reactions.
• Ligand & Catalyst Development: Employed in the preparation of specialized fluorinated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	3-Fluoro-2-Iodotoluene
CAS No.	883502-14-5
Molecular Formula	C7H6FI
Molecular Weight	236.03 g/mol
Synonyms	2-Iodo-3-fluorotoluene; 1-Fluoro-2-iodo-3-methylbenzene; 3-Methyl-2-iodofluorobenzene; 3-Fluoro-2-iodo-1-methylbenzene; Toluene, 3-fluoro-2-iodo-; 883502-14-5 (CAS); 2-Iodo-3-fluoro-1-methylbenzene; 3-Fluoro-o-iodotoluene
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Iodotoluene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality systems are designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.