Description

2-Thiophenesulfonyl Chloride, 5-Propyl- is a specialized organosulfur building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key sulfonylation reagent, enabling the introduction of the thiophene-2-sulfonyl moiety into target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the thiophene sulfonyl group confers specific biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of advanced polymers and conductive materials with tailored electronic properties.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes and molecular tags for studying enzyme function and protein interactions.
• Ligand and Catalyst Development: Utilized to construct sophisticated ligands for transition metal catalysis and organocatalysts.
• Custom Synthesis and Contract Manufacturing: A key reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Thiophenesulfonyl Chloride, 5-Propyl-
CAS No.	883146-08-5
Molecular Formula	C7H9ClO2S2
Molecular Weight	224.73 g/mol
Synonyms	5-Propylthiophene-2-sulfonyl chloride; 5-Propyl-2-thiophenesulfonyl chloride; 2-Thiophenesulfonyl chloride, 5-propyl-; 5-n-Propylthiophene-2-sulfonyl chloride; 5-Propylthiophene-2-sulphonyl chloride; 883146-08-5; 5-propylthiophene-2-sulfonylchloride
EINECS	Contact for details

Quality Control

Our production of 2-Thiophenesulfonyl Chloride, 5-Propyl- adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.