Description

3-Bromo-4-Trifluoromethoxybenzenesulfonyl Chloride is a high-value, multi-functional chemical building block essential for advanced organic synthesis. Its core value lies in its reactive sulfonyl chloride group, which facilitates the introduction of the sulfonamide moiety, a key pharmacophore in many active pharmaceutical ingredients. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel sulfonamide-based compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) containing sulfonamide functional groups, which are prevalent in drugs for hypertension, antibacterial, and anticancer applications.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the sulfonamide structure can confer specific biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, such as sulfonated polymers for ion-exchange membranes or high-performance materials.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling or modifying biomolecules (proteins, enzymes) in biochemical research and probe development.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where the bromo and trifluoromethoxy groups influence color and stability properties.

Basic Information

Product Name	3-Bromo-4-Trifluoromethoxybenzenesulfonyl Chloride
CAS No.	883146-06-3
Molecular Formula	C7H3BrClF3O3S
Molecular Weight	339.51 g/mol
Synonyms	3-Bromo-4-(trifluoromethoxy)benzenesulfonyl chloride; 1-Bromo-2-(trifluoromethoxy)-4-(chlorosulfonyl)benzene; 4-Bromo-α,α,α-trifluoro-3-methoxybenzenesulfonyl chloride; Benzenesulfonyl chloride, 3-bromo-4-(trifluoromethoxy)-; 3-Bromo-4-trifluoromethoxybenzene-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Trifluoromethoxybenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.