Description

3-Methoxybenzenesulfonyl Fluoride is a specialized organosulfur compound featuring a sulfonyl fluoride functional group. This reactive moiety makes it a valuable building block in organic synthesis, particularly for the development of pharmaceuticals, agrochemicals, and advanced materials. It is primarily sought after by research and development chemists and process engineers in the fine chemical and pharmaceutical industries for creating sulfonamide derivatives and as a probe in chemical biology.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of biologically active sulfonamide compounds used in drug discovery and development.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides that incorporate sulfonyl groups.
• Chemical Biology Probe: Utilized in activity-based protein profiling (ABPP) to label and study serine hydrolases and other enzymes due to its reactive sulfonyl fluoride group.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced functional materials.
• Organic Synthesis Building Block: Employed in Suzuki-Miyaura cross-coupling and other metal-catalyzed reactions to introduce the 3-methoxyphenylsulfonyl moiety into complex molecules.
• Fluorination Reagent Precursor: Acts as a precursor for generating other fluorinating agents or for introducing fluorine atoms in specific molecular contexts.

Basic Information

Product Name	3-Methoxybenzenesulfonyl Fluoride
CAS No.	882670-26-0
Molecular Formula	C7H7FO3S
Molecular Weight	190.19 g/mol
Synonyms	m-Methoxybenzenesulfonyl Fluoride; 3-Methoxyphenylsulfonyl Fluoride; 1-Methoxy-3-(fluorosulfonyl)benzene; 3-Methoxybenzene-1-sulfonyl Fluoride; AS-13638; BBL011232; SCHEMBL188395; CTK8G0113
EINECS	Contact for details

Quality Control

Our 3-Methoxybenzenesulfonyl Fluoride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for all tested parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions, preferably in a desiccator. Keep away from strong bases and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.