Description

5-(5-Chloro-2-Hydroxyphenyl)-n-[3-(Trifluoromethyl)Phenyl]-1H-Pyrazole-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for new chemical entities.

Application

• Key intermediate in the research and synthesis of novel pharmaceutical candidates, especially kinase inhibitors and other targeted therapies.
• Building block for medicinal chemistry programs, enabling structure-activity relationship (SAR) studies.
• Precursor in the development of agrochemicals, such as herbicides and fungicides with specific activity.
• Used in academic and industrial R&D for exploring new heterocyclic compounds with biological activity.
• Potential intermediate for dye and pigment research, leveraging its conjugated aromatic system.
• Starting material for custom synthesis and contract manufacturing of specialized fine chemicals.

Basic Information

Product Name	5-(5-Chloro-2-Hydroxyphenyl)-n-[3-(Trifluoromethyl)Phenyl]-1H-Pyrazole-3-Carboxamide
CAS No.	879463-35-1
Molecular Formula	C17H11ClF3N3O2
Molecular Weight	381.74 g/mol
Synonyms	5-(5-Chloro-2-hydroxyphenyl)-N-[3-(trifluoromethyl)phenyl]-1H-pyrazole-3-carboxamide; 1H-Pyrazole-3-carboxamide, 5-(5-chloro-2-hydroxyphenyl)-N-[3-(trifluoromethyl)phenyl]-; 879463-35-1; 5-(5-Chloro-2-hydroxyphenyl)-N-(3-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxamide; N-(3-(Trifluoromethyl)phenyl)-5-(5-chloro-2-hydroxyphenyl)-1H-pyrazole-3-carboxamide
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support compliance with cGMP and ISO 9001 standards for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.