Description

11,12-cis-13,14-Dihydroretinol is a specialized derivative of vitamin A, representing a specific stereoisomer of dihydroretinol. This compound is of significant interest in advanced biochemical research and pharmaceutical development due to its unique structural configuration and potential biological activity. It serves as a critical intermediate or reference standard for scientists and manufacturers in the life sciences sector. Key industries that utilize this high-purity chemical include pharmaceutical R&D, nutraceutical development, and academic research institutions focused on retinoid metabolism and signaling pathways.

Application

• Pharmaceutical Research & Development: Used as a key intermediate or building block in the synthesis of novel retinoid-based therapeutics targeting skin disorders, cancer, and other metabolic diseases.
• Reference Standard for Analytical Chemistry: Serves as a high-purity certified reference material (CRM) for method development, validation, and quality control in HPLC, LC-MS, and other analytical techniques.
• Biochemical Studies: Employed in academic and industrial research to investigate the structure-activity relationships (SAR) of retinoids, their metabolism, and interactions with cellular receptors.
• Nutraceutical and Cosmetic Ingredient Development: Acts as a precursor or model compound for developing advanced skincare and cosmetic formulations that leverage retinoid activity.
• Metabolic Pathway Analysis: Utilized as a tracer or standard in studies examining the enzymatic conversion and biological fate of vitamin A derivatives.

Basic Information

Product Name	11,12-cis-13,14-Dihydroretinol
CAS No.	879295-61-1
Molecular Formula	C₂₀H₃₀O
Molecular Weight	286.45 g/mol
Synonyms	(11Z,13E)-11,12-Dihydroretinol; (11Z,13E)-11,12-Dihydro-13,14-dihydroretinol; 11-cis-13,14-Dihydroretinol; Vitamin A derivative; Dihydrovitamin A alcohol (specific isomer); all-trans-13,14-Dihydroretinol isomer; Retinoid intermediate
EINECS	Contact for details

Quality Control

Our 11,12-cis-13,14-Dihydroretinol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (NMR, IR) and purity assessment by HPLC to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We adhere to cGMP principles where applicable to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or CoA. For long-term storage, keep the primary container in a freezer at -20°C. The material is light-sensitive and easily oxidized; avoid repeated warming to room temperature and minimize headspace in opened containers.

Specification

Item	Specification
Appearance	Yellow to pale orange viscous oil or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0% (Area %)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.