Description

4-[(4-Fluorophenyl)Amino]Piperidine-4-Carboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperidine-carboxamide scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) agents, kinase inhibitors, and other therapeutic small molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: Serves as a core structural component in the synthesis of potential kinase inhibitors for oncology and inflammatory diseases.
• CNS Drug Discovery: Employed in the synthesis of compounds targeting neurological pathways, such as those for pain management or neurodegenerative disorders.
• Chemical Biology Probes: Utilized to create tool compounds for studying specific biological processes and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring this specific, high-value chemical moiety.

Basic Information

Product Name	4-[(4-Fluorophenyl)Amino]Piperidine-4-Carboxamide
CAS No.	878441-19-1
Molecular Formula	C12H16FN3O
Molecular Weight	237.28 g/mol
Synonyms	4-[(4-Fluorophenyl)amino]piperidine-4-carboxamide; 4-Amino-N-(4-fluorophenyl)piperidine-4-carboxamide; 4-[(4-Fluoroanilino)piperidine-4-carboxamide; 1-(4-Fluorophenyl)-1,4-diazepane-5-carboxamide; 4-Carbamoyl-4-[(4-fluorophenyl)amino]piperidine; 878441-19-1; 4-Fluorophenylamino piperidine carboxamide
EINECS	Contact for details

Quality Control

Our 4-[(4-Fluorophenyl)Amino]Piperidine-4-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.