Description

2-Methyl-5-(2-Oxo-Pyrrolidin-1-Yl)-Benzenesulfonyl Chloride is a high-purity, specialized sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. Its core value lies in its reactive sulfonyl chloride group, which enables efficient sulfonylation and sulfonamide formation under controlled conditions. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing novel active molecules and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Biology Probe Development: Used to create sulfonamide-based probes for studying enzyme function and protein-protein interactions.
• Material Science Research: Intermediate for synthesizing specialized polymers and functional materials with specific surface properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development-scale batches.

Basic Information

Product Name	2-Methyl-5-(2-Oxo-Pyrrolidin-1-Yl)-Benzenesulfonyl Chloride
CAS No.	878433-23-9
Molecular Formula	C12H14ClNO3S
Molecular Weight	287.76 g/mol
Synonyms	1-(4-Methyl-3-sulfonylchloridophenyl)-2-pyrrolidinone; 5-(2-Oxo-1-pyrrolidinyl)-2-methylbenzenesulfonyl chloride; 2-Methyl-5-(2-oxopyrrolidin-1-yl)benzenesulfonyl chloride; 1-[3-(Chlorosulfonyl)-4-methylphenyl]pyrrolidin-2-one; 878433-23-9; 2-Methyl-5-(2-oxo-1-pyrrolidinyl)benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(2-Oxo-Pyrrolidin-1-Yl)-Benzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure compliance with exacting R&D and pre-clinical standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to prevent decomposition. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.