Description

2,3-Dibromo-5-Fluoropyridine is a high-purity halogenated pyridine derivative, serving as a critical multi-functional building block in advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the fluorine and bromine atoms contribute to biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactivity of the bromine atoms, enabling rapid diversification of molecular scaffolds.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.
• Ligand Synthesis: Used to prepare complex chelating ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Detail
Product Name	2,3-Dibromo-5-Fluoropyridine
CAS No.	878207-82-0
Molecular Formula	C5H2Br2FN
Molecular Weight	274.88 g/mol
Synonyms	5-Fluoro-2,3-dibromopyridine; 2,3-Dibromo-5-fluoropyridine; 5-Fluoro-2,3-dibromopyridine; Fluoropyridine dibromide derivative; Pyridine, 2,3-dibromo-5-fluoro-; DBFP (abbreviation)
EINECS	Contact for details

Quality Control

Every batch of 2,3-Dibromo-5-Fluoropyridine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.