Description

Methyl 3-Fluoroisonicotinate CAS NO 876919-08-3 is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive ester moiety attached to a fluorinated heterocyclic core, enabling precise molecular modifications. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atom can improve metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its conjugated pyridine system.
• Fluorine Chemistry Studies: Acts as a model compound for studying the effects of fluorine substitution on the reactivity and physicochemical properties of heteroaromatic esters.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in proprietary client synthesis projects.

Basic Information

Product Name	Methyl 3-Fluoroisonicotinate
CAS No.	876919-08-3
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	3-Fluoroisonicotinic acid methyl ester; Methyl 3-fluoropyridine-4-carboxylate; 4-Pyridinecarboxylic acid, 3-fluoro-, methyl ester; 3-Fluoro-4-(methoxycarbonyl)pyridine; 3-Fluoropyridine-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Fluoroisonicotinate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for research and process chemistry. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.