Description

1-Methyl-1H-Indole-4-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a key synthetic intermediate. This compound is critical for introducing the 1-methylindole-4-sulfonyl moiety into target molecules, enabling the development of novel chemical entities. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as medicinal chemistry, chemical biology, and the synthesis of functional polymers.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in the development of enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in creating novel active ingredients for crop protection agents, leveraging its reactive sulfonyl chloride group.
• Chemical Biology Probes: Serves as a reagent for labeling proteins or other biomolecules to study biological pathways and interactions.
• Material Science: Employed in the synthesis of specialty polymers and advanced organic materials with specific electronic or structural properties.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for fine chemical producers offering bespoke synthesis services.

Basic Information

Product Name	1-Methyl-1H-Indole-4-Sulfonyl Chloride
CAS No.	876316-36-8
Molecular Formula	C9H8ClNO2S
Molecular Weight	229.68 g/mol
Synonyms	1-Methylindole-4-sulfonyl chloride; 4-(Chlorosulfonyl)-1-methyl-1H-indole; 1-Methyl-4-indolesulfonyl chloride; 1H-Indole-4-sulfonyl chloride, 1-methyl-; 876316-36-8
EINECS	Contact for details

Quality Control

Our 1-Methyl-1H-Indole-4-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and reactive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.