Description

6-Bromo-3-(2-Fluorophenyl)-[1,2,4]Triazolo[4,3-A]Pyridine is a high-value, heterocyclic organic compound featuring a fused triazolopyridine core substituted with bromine and a fluorinated phenyl group. This specific molecular architecture makes it a critical pharmaceutical intermediate and research chemical for medicinal chemistry programs. It is primarily sought after by R&D and process development teams in the pharmaceutical, agrochemical, and advanced material sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for lead optimization and discovery.
• Agrochemical Development: Serves as a precursor for novel active ingredients in crop protection and pesticide formulations.
• Chemical Biology Probe Synthesis: Utilized to create molecular tools for studying biological pathways and target validation.
• Material Science: Potential precursor for organic electronic materials or metal-organic frameworks (MOFs) due to its rigid, heteroaromatic structure.

Basic Information

Product Name	6-Bromo-3-(2-Fluorophenyl)-[1,2,4]Triazolo[4,3-A]Pyridine
CAS No.	876300-81-1
Molecular Formula	C12H7BrFN3
Molecular Weight	292.11 g/mol
Synonyms	6-Bromo-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine; 6-Bromo-3-(o-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine; [1,2,4]Triazolo[4,3-a]pyridine, 6-bromo-3-(2-fluorophenyl)-; 876300-81-1; 6-Bromo-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-a]pyridine; 6-Bromo-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine
EINECS	Contact for details

Quality Control

Our production of 6-Bromo-3-(2-Fluorophenyl)-[1,2,4]Triazolo[4,3-A]Pyridine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for advanced intermediates and can tailor quality documentation to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.