Description

2-Bromo-5-(Trifluoromethyl)Benzyl Bromide is a versatile and highly functionalized benzyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of bromine and trifluoromethyl substituents, which enables precise molecular construction and the introduction of desirable physicochemical properties into target compounds. This intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioavailability and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized phosphine ligands and organometallic catalysts used in cross-coupling reactions.
• Material Science: Employed in the synthesis of monomers and polymers for specialty materials, including liquid crystals and organic semiconductors.
• Chemical Biology Probes: Useful for the site-specific functionalization of biomolecules and the development of molecular probes for diagnostic applications.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	2-Bromo-5-(Trifluoromethyl)Benzyl Bromide
CAS No.	875664-32-7
Molecular Formula	C8H5Br2F3
Molecular Weight	317.93 g/mol
Synonyms	α,2-Dibromo-α-(trifluoromethyl)toluene; 1-(Bromomethyl)-2-bromo-5-(trifluoromethyl)benzene; (2-Bromo-5-(trifluoromethyl)phenyl)methyl bromide; 2-Bromo-α-(bromomethyl)-α,α,α-trifluorotoluene; Benzene, 1-(bromomethyl)-2-bromo-5-(trifluoromethyl)-; 2-Bromo-5-trifluoromethylbenzyl bromide
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-(Trifluoromethyl)Benzyl Bromide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality commitment aligns with cGMP principles where applicable, ensuring reliable and consistent performance in your processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.