Description

1-Fluoro-4-Iodo-2-Isopropyl-5-Methoxybenzene is a high-purity, multi-functional halogenated benzene derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring fluorine, iodine, and methoxy substituents, makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its halogenated aromatic core.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Negishi couplings.
• Chemical Synthesis: Employed as a versatile building block for introducing fluorine and iodine groups into more complex aromatic systems.
• R&D and Process Chemistry: Essential for route scouting, process optimization, and scale-up activities in fine chemical production.

Basic Information

Product Name	1-Fluoro-4-Iodo-2-Isopropyl-5-Methoxybenzene
CAS No.	875446-57-4
Molecular Formula	C10H12FIO
Molecular Weight	294.11 g/mol
Synonyms	4-Fluoro-2-Iodo-5-Isopropylanisole; 5-Fluoro-2-Iodo-4-Isopropylanisole; 2-Isopropyl-1-fluoro-4-iodo-5-methoxybenzene; 1-Fluoro-4-iodo-2-isopropyl-5-methoxy-benzene; Benzene, 1-fluoro-4-iodo-2-(1-methylethyl)-5-methoxy-; 875446-57-4 (CAS); 4-Iodo-2-isopropyl-5-methoxyfluorobenzene
EINECS	Contact for details

Quality Control

Our 1-Fluoro-4-Iodo-2-Isopropyl-5-Methoxybenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. For custom synthesis or specific purity requirements (e.g., >98%, >99%), please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.