Description

3-Fluoro-2-Methylbenzenesulfonyl Chloride is a versatile and high-purity sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its reactivity as a sulfonylation agent, enabling the introduction of the sulfonyl group to construct complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and pesticides that require the sulfonyl moiety for bioactivity.
• Material Science Research: Employed in the development of specialty polymers, dyes, and functional materials where sulfonyl groups modify physical properties.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling proteins or modifying biomolecules in research applications.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for fine chemical and custom synthesis houses producing bespoke compounds for clients.

Basic Information

Product Name	3-Fluoro-2-Methylbenzenesulfonyl Chloride
CAS No.	875166-92-0
Molecular Formula	C7H6ClFO2S
Molecular Weight	208.64 g/mol
Synonyms	2-Methyl-3-fluorobenzenesulfonyl chloride; 3-Fluoro-o-toluenesulfonyl chloride; 1-Fluoro-2-methyl-6-(chlorosulfonyl)benzene; 3-Fluoro-2-methylbenzene-1-sulfonyl chloride; 2-Methyl-3-fluorophenylsulfonyl chloride; 3-F-2-Me-BsCl; 875166-92-0
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Methylbenzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent hydrolysis and degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.