Description

5-Bromo-4-Fluoro-2-Methylbenzenesulfonyl Chloride is a high-purity, multi-functional sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. Its value lies in its reactive sulfonyl chloride group and strategically placed halogen substituents, enabling precise molecular modifications. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially sulfonamide-based drugs.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Used in the creation of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation, labeling biomolecules, or developing activity-based probes.
• Dye & Pigment Manufacturing: Intermediate in the production of complex colorants and functional dyes.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex aromatic systems.

Basic Information

Product Name	5-Bromo-4-Fluoro-2-Methylbenzenesulfonyl Chloride
CAS No.	874804-12-3
Molecular Formula	C7H5BrClFO2S
Molecular Weight	287.53 g/mol
Synonyms	2-Methyl-5-bromo-4-fluorobenzenesulfonyl chloride; 5-Bromo-4-fluoro-o-toluenesulfonyl chloride; 1-Bromo-2-fluoro-4-(chlorosulfonyl)-5-methylbenzene; 4-Fluoro-5-bromo-2-methylbenzenesulfonyl chloride; Benzenesulfonyl chloride, 5-bromo-4-fluoro-2-methyl-; 5-Br-4-F-2-Me-PhSO2Cl
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-4-Fluoro-2-Methylbenzenesulfonyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C (refrigerated) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.