Description

5-Bromo-2-Fluoro-4-Methylbenzenesulfonyl Chloride is a high-purity, multi-functional sulfonyl chloride derivative essential for advanced organic synthesis. This compound serves as a critical building block for introducing the sulfonamide moiety into target molecules, enabling the development of novel chemical entities. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Research: Used in the creation of specialty polymers and functional materials requiring sulfonyl groups.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying protein function and interactions.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs for the production of bespoke intermediates under cGMP or research-grade conditions.

Basic Information

Product Name	5-Bromo-2-Fluoro-4-Methylbenzenesulfonyl Chloride
CAS No.	874801-49-7
Molecular Formula	C7H5BrClFO2S
Molecular Weight	287.53 g/mol
Synonyms	4-Methyl-5-bromo-2-fluorobenzenesulfonyl chloride; 2-Fluoro-4-methyl-5-bromobenzenesulfonyl chloride; 5-Bromo-2-fluoro-p-toluenesulfonyl chloride; 874801-49-7; Benzenesulfonyl chloride, 5-bromo-2-fluoro-4-methyl-; 5-Bromo-2-fluoro-4-methylbenzene-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoro-4-Methylbenzenesulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring research-grade to cGMP-quality material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.