Description

2-Bromo-4,5-Difluorobenzenesulfonyl Chloride is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. Its core value lies in its reactive sulfonyl chloride and halogenated aromatic structure, enabling precise molecular construction in complex chemical pathways. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, leveraging its difluoro and bromo substituents for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced functional materials.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the development of chemical probes targeting specific enzymes or proteins.
• Dye & Pigment Manufacturing: Employed in the synthesis of complex, halogenated aromatic dyes and colorants with enhanced properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Bromo-4,5-Difluorobenzenesulfonyl Chloride
CAS No.	874784-11-9
Molecular Formula	C6H2BrClF2O2S
Molecular Weight	291.50 g/mol
Synonyms	2-Bromo-4,5-difluorobenzenesulfonyl chloride; Benzenesulfonyl chloride, 2-bromo-4,5-difluoro-; 4,5-Difluoro-2-bromobenzenesulfonyl chloride; 2-Bromo-4,5-difluorophenylsulfonyl chloride; 874784-11-9 (CAS); 2-Br-4,5-diF-PhSO2Cl
EINECS	Contact for details

Quality Control

Our 2-Bromo-4,5-Difluorobenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee reliable and consistent performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.