Description

2,4-Dichloro-5-Fluorobenzenesulfonyl Chloride is a key sulfonyl chloride derivative and a versatile high-purity building block in advanced organic synthesis. Its value lies in its dual functionality, serving as a critical precursor for the development of complex sulfonamides and other active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the sulfonyl pharmacophore into novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of sulfonamide-based drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides that utilize the sulfonyl moiety for biological activity.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced functional materials.
• Chemical Research: Employed in academic and industrial R&D for exploring new reaction pathways and creating compound libraries for screening.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex sulfonated dyes and colorants.

Basic Information

Product Name	2,4-Dichloro-5-Fluorobenzenesulfonyl Chloride
CAS No.	874773-65-6
Molecular Formula	C6H2Cl2FO2S
Molecular Weight	247.05 g/mol
Synonyms	5-Fluoro-2,4-dichlorobenzenesulfonyl chloride; 2,4-Dichloro-5-fluorobenzene-1-sulfonyl chloride; 1,3-Dichloro-4-fluoro-6-(chlorosulfonyl)benzene; Benzenesulfonyl chloride, 2,4-dichloro-5-fluoro-; 2,4-Dichloro-5-fluorophenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5-Fluorobenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.