Description

n-Boc-S-Bzl-L-Cys-Gly-Obzl-13C2,15N is a stable isotope-labeled derivative of a protected cysteine-glycine dipeptide, essential for advanced research and development. This compound is a critical building block for synthesizing isotopically labeled peptides, enabling precise metabolic, pharmacokinetic, and proteomic studies. It is primarily utilized by pharmaceutical R&D teams, contract research organizations (CROs), and academic institutions focused on drug discovery and biomarker analysis.

Application

• Isotope-Labeled Peptide Synthesis: Serves as a key intermediate for incorporating stable isotopes (13C, 15N) into custom peptides for mass spectrometry-based quantification.
• Metabolic Pathway Tracing: Used in the development of labeled peptide probes to study drug metabolism, protein turnover, and cellular pathways.
• Internal Standard Production: Essential for creating high-purity internal standards for Liquid Chromatography-Mass Spectrometry (LC-MS/MS) bioanalytical assays, ensuring accurate quantification of target analytes.
• Proteomics Research: Enables the synthesis of isotopically labeled peptides for use in quantitative proteomics, such as SILAC (Stable Isotope Labeling by Amino acids in Cell culture) or targeted proteomics workflows.
• Pharmaceutical Development: Supports the discovery and development phase of peptide-based therapeutics by providing a labeled precursor for absorption, distribution, metabolism, and excretion (ADME) studies.
• Bioconjugation and Chemical Biology: The protected thiol (S-Bzl) and carboxylic acid (Obzl) groups allow for selective deprotection and further functionalization in complex bioconjugation strategies.

Basic Information

Product Name	n-Boc-S-Bzl-L-Cys-Gly-Obzl-13C2,15N
CAS No.	874462-69-8
Molecular Formula	C24H2813C215N1O6S1
Molecular Weight	~503.6 g/mol (for labeled form)
Synonyms	(2S)-2-[[(2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-(phenylmethanesulfanyl)propanoyl]amino]acetic acid benzyl ester-13C2,15N; N-[(Benzyloxy)carbonyl]-S-benzyl-L-cysteinylglycine benzyl ester-13C2,15N; Boc-Cys(Bzl)-Gly-OBzl-13C2,15N; tert-Butoxycarbonyl-S-benzyl-L-cysteinylglycine benzyl ester-13C2,15N; Labeled Boc-Cys(Bzl)-Gly-OBzl; Isotope-labeled protected dipeptide; [13C2,15N]-Boc-Cys(Bzl)-Gly-OBzl
EINECS	Contact for details

Quality Control

Our n-Boc-S-Bzl-L-Cys-Gly-Obzl-13C2,15N is manufactured under strict quality systems to ensure high isotopic and chemical purity, critical for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and identity confirmation via advanced spectroscopic and chromatographic methods. We adhere to cGMP principles for production and quality control, ensuring traceability and consistency for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, containers should be allowed to equilibrate to room temperature before opening to minimize moisture ingress. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom %
Isotopic Enrichment (15N)	≥ 99 atom %
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.