Description

5-(Benzylcarbamoyl)-2-Fluorobenzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its dual functionality, serving as a versatile intermediate in cross-coupling reactions and as a key synthon for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel biaryl compounds with potential therapeutic activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by enabling the construction of complex fluorinated aromatic structures.
• Material Science: Serves as a monomer or functionalization agent in the synthesis of organic electronic materials, such as polymers for OLEDs or sensors.
• Chemical Biology & Proteomics: Utilized as a molecular probe or linker due to its boronic acid group's affinity for diols, facilitating bioconjugation and target identification.
• Catalyst & Ligand Development: Acts as a starting material for creating novel palladium catalyst ligands or organocatalysts.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses serving the life sciences industry, enabling rapid prototyping of candidate molecules.

Basic Information

Product Name	5-(Benzylcarbamoyl)-2-Fluorobenzeneboronic Acid
CAS No.	874289-53-9
Molecular Formula	C14H13BFNO3
Molecular Weight	273.07 g/mol
Synonyms	2-Fluoro-5-[(phenylmethyl)carbamoyl]benzeneboronic Acid; [2-Fluoro-5-(benzylcarbamoyl)phenyl]boronic Acid; 5-(Benzylaminocarbonyl)-2-fluorobenzeneboronic Acid; B-[2-Fluoro-5-[(phenylmethyl)carbamoyl]phenyl]boronic Acid; 2-Fluoro-N-benzyl-5-boronobenzamide; 874289-53-9; 5-Carbamoyl-2-fluorobenzeneboronic Acid Benzyl Ester
EINECS	Contact for details

Quality Control

Our production of 5-(Benzylcarbamoyl)-2-Fluorobenzeneboronic Acid adheres to stringent internal quality standards, ensuring batch-to-batch consistency and high purity suitable for research and commercial synthesis. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee material integrity for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.