Description

3-(4-Fluorobenzylcarbamoyl)Phenylboronic Acid is a specialized organoboron compound featuring both a boronic acid and a fluorinated benzylcarbamoyl moiety. This bifunctional structure makes it a valuable high-purity building block for advanced synthesis, particularly in pharmaceutical research and materials science. It is primarily utilized by R&D chemists and process development scientists in the life sciences and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting kinase inhibition or requiring Suzuki-Miyaura cross-coupling reactions.
• Bioconjugation & Probe Development: Used in creating fluorescent probes, affinity labels, and other diagnostic tools that leverage boronic acid chemistry for binding to diols or specific biological targets.
• Materials Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers, covalent organic frameworks (COFs), and other functional materials.
• Agrochemical Synthesis: Employed in the research and development of novel crop protection agents and herbicides that incorporate fluorinated aromatic systems.
• Chemical Biology: Utilized in the study of enzyme mechanisms and the development of enzyme inhibitors where the boronic acid group acts as a transition-state analog.

Basic Information

Product Name	3-(4-Fluorobenzylcarbamoyl)Phenylboronic Acid
CAS No.	874288-19-4
Molecular Formula	C14H13BFNO3
Molecular Weight	273.07 g/mol
Synonyms	[3-[(4-Fluorophenyl)methylcarbamoyl]phenyl]boronic acid; 3-[(4-Fluorobenzyl)carbamoyl]benzeneboronic acid; 3-Carbamoylphenylboronic acid, N-(4-fluorobenzyl)-; Boronic acid, B-[3-[[(4-fluorophenyl)methyl]amino]carbonyl]phenyl]-; 3-(4-Fluorobenzylaminocarbonyl)phenylboronic acid
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorobenzylcarbamoyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high-purity standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.