Description

tert-Butyl 2-(Chlorosulfonyl)-1H-Indole-1-Carboxylate is a high-value, multi-functional chemical building block designed for advanced synthetic chemistry. This compound is critical for researchers and manufacturers requiring precise, reactive intermediates to construct complex molecular architectures. It is primarily utilized by the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel indole-based drug candidates, including kinase inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides with enhanced efficacy.
• Material Science Research: Serves as a reactive monomer or cross-linking agent for creating specialty polymers and advanced organic materials.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	tert-Butyl 2-(Chlorosulfonyl)-1H-Indole-1-Carboxylate
CAS No.	872983-77-2
Molecular Formula	C₁₃H₁₄ClNO₄S
Molecular Weight	315.77 g/mol
Synonyms	1-Boc-2-(chlorosulfonyl)indole; tert-Butyl 2-chlorosulfonyl-1H-indole-1-carboxylate; 2-(Chlorosulfonyl)-1H-indole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-2-(chlorosulfonyl)indole; Boc-2-(chlorosulfonyl)indole; 872983-77-2; 1H-Indole-1-carboxylic acid, 2-(chlorosulfonyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(Chlorosulfonyl)-1H-Indole-1-Carboxylate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We support development and commercial projects with material suitable for research use and can supply grades that meet the stringent requirements of cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.