Description

Epelsiban is a selective oxytocin receptor antagonist, representing a significant advancement in the field of reproductive medicine and neuroendocrine research. This high-purity compound is critical for researchers and pharmaceutical developers investigating uterine contractility and social behavior modulation. It is primarily utilized in the development of therapeutic agents for preterm labor and as a vital pharmacological tool in neuroscience. Epelsiban CAS NO 872599-83-2 offers a reliable standard for assay validation and preclinical studies, ensuring data integrity and reproducibility.

Application

• Pharmaceutical R&D: Core intermediate or active pharmaceutical ingredient (API) in the development of tocolytic agents for the management of preterm labor.
• Neuroscience Research: Selective pharmacological tool for studying the role of the oxytocin system in social behaviors, anxiety, and stress response.
• Biochemical Assays: Reference standard for in vitro receptor binding studies and functional assays to evaluate oxytocin receptor antagonism.
• Preclinical Studies: Used in animal models to investigate uterine physiology and the efficacy of potential therapeutic candidates.
• Process Chemistry: Serves as a key building block in the synthetic pathways for more complex oxytocin-related analogs.

Basic Information

Product Name	Epelsiban
CAS No.	872599-83-2
Molecular Formula	C₂₉H₄₀N₄O₅S
Molecular Weight	556.72 g/mol
Synonyms	GSK557296; (2S,4R)-1-[(2S)-2-Amino-3,3-bis(4-fluorophenyl)propanoyl]-4-{[(3S,6R)-6-benzyl-1-(2,2,2-trifluoroacetyl)piperidin-3-yl]methyl}-N-(4-fluorobenzyl)piperidine-2-carboxamide; 1-[(2S)-2-Amino-3,3-bis(4-fluorophenyl)propanoyl]-4-{[(3S,6R)-6-benzyl-1-(2,2,2-trifluoroacetyl)piperidin-3-yl]methyl}-N-[(4-fluorophenyl)methyl]-L-prolinamide; Oxytocin Receptor Antagonist GSK557296
EINECS	Contact for details

Quality Control

Every batch of Epelsiban is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and potency. We provide full traceability and Certificates of Analysis (COA) that detail specifications including assay, chiral purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring consistency and reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.