Description

Ro 3306 CAS NO 872573-93-8 is a potent and selective cell-permeable inhibitor of cyclin-dependent kinase 1 (CDK1). This compound matters for researchers and developers as it provides a critical tool for probing cell cycle regulation, apoptosis, and DNA damage response pathways. It is needed by professionals in pharmaceutical R&D, academic biochemistry and oncology research, and biotechnology companies focused on developing novel cancer therapeutics.

Application

• Biochemical Research: A key reagent for studying the specific roles of CDK1 in cell cycle progression, mitosis, and checkpoint control.
• Oncology & Cancer Research: Used to investigate the mechanisms of cell cycle arrest and apoptosis in various cancer cell lines, aiding in target validation.
• Pharmaceutical Development: Serves as a reference standard and a lead compound in the discovery and optimization of novel CDK1-targeted therapeutic agents.
• Signal Transduction Studies: Employed to dissect complex signaling networks where CDK1 activity is a critical node, particularly in DNA damage response.
• Academic & Institutional Labs: Essential for fundamental research in molecular biology, genetics, and developmental biology related to cell division.

Basic Information

Product Name	Ro 3306
CAS No.	872573-93-8
Molecular Formula	C₁₆H₁₈N₈O₂
Molecular Weight	354.37 g/mol
Synonyms	Ro-3306; 6-[[2-[(3,5-Dimethyl-1H-pyrazol-1-yl)methyl]-5-methoxy-4-pyrimidinyl]amino]-2-naphthalenecarbonitrile; CDK1 Inhibitor Ro 3306; Cyclin-Dependent Kinase 1 Inhibitor Ro3306; Ro3306; Ro 3306 (CDK1 inhibitor)
EINECS	Contact for details

Quality Control

Our Ro 3306 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications for consistent, reliable performance in your experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. Due to its hygroscopic nature, the container should be sealed under inert atmosphere or with desiccant after each use to maintain stability and potency. Allow the product to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.