Description

5-Fluoropyridin-3-Ylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its core value lies in enabling the efficient synthesis of complex fluorinated heterocycles via cross-coupling reactions, which are fundamental to pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to incorporate the 5-fluoropyridin-3-yl moiety into novel molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring fluorinated pyridine scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the fluoropyridine unit can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a building block for creating specialized ligands and organometallic catalysts used in asymmetric synthesis and other advanced catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs or conductive polymers, where fluorinated aromatic systems can tune electronic properties.
• Chemical Biology & Probe Design: Utilized in the construction of molecular probes and bio-conjugates for studying biological systems and diagnostic applications.

Basic Information

Product Name	5-Fluoropyridin-3-Ylboronic Acid
CAS No.	872041-86-6
Molecular Formula	C5H5BFNO2
Molecular Weight	140.91 g/mol
Synonyms	(5-Fluoropyridin-3-yl)boronic acid; 3-Borono-5-fluoropyridine; 5-Fluoro-3-pyridineboronic acid; 5-Fluoropyridine-3-boronic acid; 3-Pyridineboronic acid, 5-fluoro-; 5-Fluoro-3-pyridinylboronic acid; B-(5-Fluoropyridin-3-yl)boronic acid
EINECS	Contact for details

Quality Control

Our 5-Fluoropyridin-3-Ylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive cross-coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.