Description

2-Methylpyridine-3-Sulfonyl Chloride is a versatile and reactive sulfonyl chloride derivative used as a key building block in advanced organic synthesis. Its primary value lies in its ability to introduce the 2-methylpyridine-3-sulfonyl moiety, a crucial functional group for modulating the physicochemical and biological properties of target molecules. This intermediate is particularly essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is employed in the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the sulfonamide linkage is a common pharmacophore.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and functional materials.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes and labeling reagents for proteomics and diagnostic applications.
• Ligand and Catalyst Development: Utilized to create novel ligands for metal complexes and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	2-Methylpyridine-3-Sulfonyl Chloride
CAS No.	872001-95-1
Molecular Formula	C6H6ClNO2S
Molecular Weight	191.64 g/mol
Synonyms	3-Picoline-2-sulfonyl chloride; 2-Methyl-3-pyridinesulfonyl chloride; 2-Methylpyridine-3-sulfonyl chloride; 3-(Chlorosulfonyl)-2-methylpyridine; 2-Picoline-3-sulfonyl chloride; 2-Methyl-3-sulfonylchloropyridine
EINECS	Contact for details

Quality Control

Our 2-Methylpyridine-3-Sulfonyl Chloride is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.