Description

4-Chloro-3-(T-Butylcarbamoyl)Phenylboronic Acid is a high-value boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its molecular structure, featuring both a boronic acid group and a protected amide moiety, makes it an essential reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogen and boronic acid functionalities for structure-activity relationship (SAR) studies.
• Material Science: Serves as a monomer or functionalization agent in the synthesis of organic electronic materials, such as polymers for OLEDs.
• Chemical Biology & Proteomics: Employed as a molecular probe or linker due to its specific reactivity, useful in bioconjugation and target identification.
• Academic & Process Chemistry: A versatile reagent for methodological development in organic synthesis and scale-up process optimization within R&D laboratories.

Basic Information

Product Name	4-Chloro-3-(T-Butylcarbamoyl)Phenylboronic Acid
CAS No.	871332-72-8
Molecular Formula	C11H15BClNO3
Molecular Weight	255.51 g/mol
Synonyms	4-Chloro-3-[(tert-butylcarbamoyl)]benzeneboronic acid; [4-Chloro-3-[(2-methylpropan-2-yl)carbamoyl]phenyl]boronic acid; 4-Chloro-N-tert-butyl-3-boronobenzamide; B-[4-Chloro-3-[(1,1-dimethylethyl)aminocarbonyl]phenyl]boronic acid; 4-Chloro-3-(tert-butylaminocarbonyl)phenylboronic acid; 4-Chloro-3-(N-tert-butylcarbamoyl)phenylboronic acid; 871332-72-8; 4-Chloro-3-(tert-butylcarbamoyl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-(T-Butylcarbamoyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.