Description

2-Fluoro-4-Formylphenylboronic Acid is a versatile and highly functionalized boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in the unique combination of a formyl group and a boronic acid moiety on a fluorinated aromatic ring, enabling precise cross-coupling and subsequent functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and advanced materials through Suzuki-Miyaura coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those requiring fluorinated biaryl structures for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating novel pesticides and herbicides where the fluorine atom and formyl group contribute to specific biological activity and environmental persistence.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where its functional groups allow for precise molecular engineering.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for creating fluorescent tags or affinity probes due to the reactivity of the aldehyde group for bioconjugation.
• Cross-Coupling Reactions: Primarily utilized in Suzuki-Miyaura cross-coupling to form carbon-carbon bonds, constructing complex aromatic systems efficiently.

Basic Information

Item	Details
Product Name	2-Fluoro-4-Formylphenylboronic Acid
CAS No.	871126-22-6
Molecular Formula	C7H6BFO3
Molecular Weight	167.93 g/mol
Synonyms	(2-Fluoro-4-formylphenyl)boronic acid; 4-Borono-3-fluorobenzaldehyde; 2-Fluoro-4-carboxybenzene boronic acid; 3-Fluoro-4-boronobenzaldehyde; 2-Fluoro-4-formylbenzeneboronic acid; 4-Formyl-2-fluorophenylboronic acid; B-(2-Fluoro-4-formylphenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Formylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.