Description

2,4-Difluoro-3-Methoxybenzaldehyde is a versatile fluorinated aromatic aldehyde building block. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, especially those containing difluoromethoxybenzene motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated organic electronic materials, contributing to improved charge transport and thermal stability.
• Functional Dye & Pigment Production: Employed in the synthesis of specialized dyes and pigments where the aldehyde group allows for further functionalization and color tuning.
• Cross-Coupling Reactions: The aldehyde and halogen substituents make it a suitable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Organic Synthesis Reagent: Used in academic and industrial research laboratories for constructing heterocyclic compounds and as a starting material for various nucleophilic addition reactions.

Basic Information

Product Name	2,4-Difluoro-3-Methoxybenzaldehyde
CAS No.	870837-66-4
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	3-Methoxy-2,4-difluorobenzaldehyde; 2,4-Difluoro-3-methoxy-benzaldehyde; 2,4-Difluoro-3-methoxybenzenecarboxaldehyde; Benzaldehyde, 2,4-difluoro-3-methoxy-; 870837-66-4
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-3-Methoxybenzaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.