Description

2-Fluoro-5-Methylbenzenesulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to act as a sulfonylation reagent, enabling the introduction of the sulfonyl functional group to create compounds with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel sulfonamide-based drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science: Employed in the creation of specialty polymers, dyes, and liquid crystals where the sulfonyl group modifies physical and chemical properties.
• Chemical Research & Development: A valuable reagent in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Peptide Modification: Can be used to modify amino acid side chains, introducing sulfonyl groups for biochemical studies.

Basic Information

Product Name	2-Fluoro-5-Methylbenzenesulfonyl Chloride
CAS No.	870704-14-6
Molecular Formula	C7H6ClFO2S
Molecular Weight	208.64 g/mol
Synonyms	2-Fluoro-5-methylbenzene-1-sulfonyl chloride; 5-Methyl-2-fluorobenzenesulfonyl chloride; Benzenesulfonyl chloride, 2-fluoro-5-methyl-; 2-Fluoro-5-methylphenylsulfonyl chloride; 870704-14-6; 2-Fluoro-5-toluenesulfonyl chloride; 2-Fluoro-5-methylbenzenesulphonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methylbenzenesulfonyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.