Description

3,5-Difluoro-4-Pyridinecarboxaldehyde is a versatile fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of fluorine atoms and an aldehyde functional group, which enable precise molecular modifications and the construction of complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the difluoropyridine moiety enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Acts as a monomer or functionalization agent in the creation of advanced polymers and electronic materials.
• Chemical Biology Probes: Utilized to synthesize fluorescent tags or molecular probes for studying biological processes.
• Custom Synthesis and Scale-Up: Serves as a starting material for contract research organizations (CROs) and custom synthesis providers for client-specific projects.

Basic Information

Product Name	3,5-Difluoro-4-Pyridinecarboxaldehyde
CAS No.	870234-98-3
Molecular Formula	C6H3F2NO
Molecular Weight	143.09 g/mol
Synonyms	4-Pyridinecarboxaldehyde, 3,5-difluoro-; 3,5-Difluoropyridine-4-carbaldehyde; 3,5-Difluoropyridine-4-carboxaldehyde; 3,5-Difluoroisonicotinaldehyde; 4-Formyl-3,5-difluoropyridine; 3,5-Difluoro-4-formylpyridine; 870234-98-3 (CAS)
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-Pyridinecarboxaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.