Description

1H-Indole-2-Carboxamide, n-[(1S)-1-[[[(1S)-3-Hydroxy-2-Oxo-1-[[(3S)-2-Oxo-3-Pyrrolidinyl]Methyl]Propyl]Amino]Carbonyl]-3-Methylbutyl]-4-Methoxy- (9Ci) is a complex, high-purity chiral organic compound of significant interest in advanced pharmaceutical research and development. Its intricate molecular architecture, featuring indole, carboxamide, and pyrrolidinone moieties, makes it a valuable key intermediate or building block for synthesizing novel therapeutic agents. This compound is primarily targeted at pharmaceutical R&D teams and fine chemical manufacturers engaged in the discovery of protease inhibitors and other biologically active molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of potential drug candidates, particularly for targeting specific enzymatic pathways.
• Protease Inhibitor Research: Used in the development and screening of novel protease inhibitors due to its structural similarity to peptide substrates.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Biochemical Research: Acts as a reference standard or tool compound in biochemical assays to study enzyme kinetics and mechanisms.
• Custom Synthesis: Provided as a starting material for contract research organizations (CROs) and CDMOs for client-specific synthetic routes.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and chemical biology.

Basic Information

Product Name	1H-Indole-2-Carboxamide, n-[(1S)-1-[[[(1S)-3-Hydroxy-2-Oxo-1-[[(3S)-2-Oxo-3-Pyrrolidinyl]Methyl]Propyl]Amino]Carbonyl]-3-Methylbutyl]-4-Methoxy- (9Ci)
CAS No.	870153-29-0
Molecular Formula	C24H32N4O6
Molecular Weight	472.54 g/mol
Synonyms	(2S)-N-[(2S)-1-[[(1S)-3-Hydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]methyl]-2-oxopropyl]amino]-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide; UNII-9Q4XH3U5Q5; 9Q4XH3U5Q5; 1H-Indole-2-carboxamide, N-[(1S)-1-[[[(1S)-3-hydroxy-2-oxo-1-[[(3S)-2-oxo-3-pyrrolidinyl]methyl]propyl]amino]carbonyl]-3-methylbutyl]-4-methoxy-; BDBM50111657; SCHEMBL233062; AKOS025147269; AS-57800
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and reliability for critical research applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, chiral purity, and impurity profiles. We support development under cGMP guidelines where required for pharmaceutical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.